Tissue-specific SMARCA4 binding at active and repressed regulatory elements during embryogenesis
نویسندگان
چکیده
منابع مشابه
Tissue-specific SMARCA4 binding at active and repressed regulatory elements during embryogenesis.
The SMARCA4 (also known as BRG1 in humans) chromatin remodeling factor is critical for establishing lineage-specific chromatin states during early mammalian development. However, the role of SMARCA4 in tissue-specific gene regulation during embryogenesis remains poorly defined. To investigate the genome-wide binding landscape of SMARCA4 in differentiating tissues, we engineered a Smarca4(FLAG) ...
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ژورنال
عنوان ژورنال: Genome Research
سال: 2014
ISSN: 1088-9051
DOI: 10.1101/gr.168930.113